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APS Nutrition Plasmagen Nitrate 200 Capsules
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List Price: $79.95
Your Price: $26.99
You Save: $52.96
Out of stock
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APS Nutrition Plasmagen Nitrate unites a unique assembly of highly synergistic
agents that are guaranteed to power your workout to a new level of
intensity, while ensuring your recovery will be the most rapid
imaginable! Combining beta-alanine and citrulline malate alone in
appropriate doses can provide you with explosive workouts with smooth
recovery. Now imagine adding the potency of gycine propionyl l-carnitine
to that blend to drive your workout intensity, endurance and performance
to supernatural levels. Then incorporate arginine ethyl ester, l-nor-valine,
and magnesium tanshinoate B to that already mind-blowing mix to obtain
the only formula of its type that can not only promise but deliver
radically new levels oxygen utilization, elevated protein synthesis,
improved glycogen synthesis, dramatically effective nitric oxide
synthesis for road-map vascularity, and mind-boggling muscle growth,
tissue repair and recovery. As an added bonus, Plasmagen Nitrate will
give you optimal antioxidant protection and improved sexual performance!
Sculpt your future today! Go Plasmagen Nitrate!
Plasmagen Nitrate delivers:
● Explosive increases in anaerobic and aerobic performance, strength,
and muscular endurance
● Radical improvements in muscle contraction and muscle growth
● Dramatic boost in oxygen utilization
● Significantly delayed onset of muscle fatigue
● Unparalleled rapid recovery
● Elevated protein synthesis leading to dense, lean muscle mass
● Enhanced nitric-oxide synthesis, producing extreme vascularity and
pump
● Improved glycogen synthesis
● Dramatic increases in fatty-acid metabolization, leading to noticeable
fat-loss
● Improvement in sexual performance
● Elevated mitochondrial function, fat metabolism, and myocardial health
● Potent antioxidant support and immune enhancement
Plasmagen Nitrate Nutritional Info:
Serving Size: 10 Capsules
Servings Per Container: 26 (Taken as directed)
PlasmaFuze Proprietary Blend: 7600mg
Beta-Alanine, L-Citruline-DL-Malate, Arginine Ethyl Ester DI-HCL, GPLC (Glycine
Propionyl L-Carnitine), L-2-Aminopentanoic Acid, Magnesium Tanshinoate
B.
Beta-Alanine
Beta-Alanine (3-aminopropanoic acid) and L-Histidine are the building
blocks of the multifunctional dipeptide, L-Carnosine (L-beta-alanyl-L-histidine).
The only naturally occurring beta amino acid (the amino group is
attached to the beta (ß) position relative to the carboxylate group),
beta-alanine is also a constituent of calcium pantothenate, or vitamin
B5. When we supplement with carnosine, or consume foods containing
carnosine, a highly active enzyme referred to as carnosinase degrades
carnosine into its precursors, beta-alanine and l-histidine. These amino
acids are subsequently absorbed into skeletal muscle cells where they
are resynthesized (or re-combined) to carnosine by an enzyme called=2
0carnosine synthase. High intensity exercise is known to produce
elevations in lactic acid concentrations as well as produce high H+
(hydrogen ions) concentrations. These increased levels lead to rapid
onset of fatigue and decreased performance. Carnosine turns out to be an
important metabolic buffer in skeletal muscle cells by promoting the
neutralization of lactic acid, thereby dramatically enhancing
performance and muscle contraction. Research has shown that skeletal
muscle concentration of carnosine promotes performance and muscle
contraction during periods of high intensity exercise.
The following is just as significant: Carnosine is found in both Type I
and Type II muscle fibers, although it is preferentially found in
fast-twitch (Type II) muscle fibers in humans. Type II muscle fibers are
those with a significant potential for growth. Type I, or slow-twitch
muscle fibers, on the other hand, have a limited capacity for growth. As
it turns out, most of us have more Type I than Type II. Yet, by
preferentially increasing carnosine concentrations in Type II muscle
fibers and stimulating their growth, we can dramatically maximize the
growth capacity of these fast-twitch fibers.
Furthermore, L-Carnosine is considered one of the most potent
antioxidants available, as it possesses the unique ability to quench the
destructive effects of a broad variety of free radicals, such as
hydroxyl radicals, super oxides, singlet oxygen, and peroxyl radicals.
L-carnosine also appears to protect cellular DNA integrity from
oxidative damage, lead ing to cell-protective effects associated with
markers of an effective anti-aging agent.
Although carnosine is made up of both beta alanine and l-histidine,
research has demonstrated that beta alanine is the limiting factor in
carnosine synthesis, as l-histidine is readily available in required
quantities in diet. This means that beta alanine supplementation is a
convenient and effective way to boost intra-cellular carnosine
concentrations. Consequently, beta-alanine supplementation delays the
onset of muscular fatigue, boosts energy levels and the efficiency of
aerobic exercise, boost endurance levels, and supports the synthesis of
nitric oxide.
So what does all this mean? Simple! With beta-alanine, you can
effectively boost cellular carnosine concentrations. This will
dramatically neutralize lactic acid and hydrogen ion levels, leading to
delayed fatigue, increased performance and endurance, dramatic strength
increases, intense muscle contractions, and radical improvements in the
development of fast-twitch muscle fibers, providing significant growth
in dense, lean mass. Beyond this, carnosine via beta-alanine provides
superior antioxidant protection, improved mitochondrial function, and
enhanced immune support. Simply one of the most potent all-round
supplements around! Plasmagen provides you with a generous per-dose
amount of this compound, matching the quantities employed in successful
clinicals.
L-Citruline-DL-Malate
Formed in the mitochondria via a combination of carbon-dioxide, ammonia,
and ornithine, Citrulline is a non-essential amino acid
intricately20involved in nitrogen balance and regulation of diverse
metabolic processes. Outside of the mitochondria, citrulline can be
converted to arginine. Citrulline malate is a salt form of citrulline,
and is formed by bonding citrulline to malic acid. Considering that
malate is a Krebs Cycle intermediate (in addition to citrate, fumarate,
succinate, and alpha ketoglutarate), the citrulline malate form unites
several cool benefits, including regulation of aerobic cellular
respiration and the generation of energy in the mitochondria. Citrulline
is vital for the detoxification and elimination of ammonia from liver
and muscle cells. More specifically, ammonia is produced in muscle cells
as a by-product of the breakdown of proteins during intense physical
exertion. This ammonia can either accumulate in the muscle cells or in
the liver, leading to toxicity and compromising the protection of cells
from dangerous ions. Via a sequence of reactions, ammonia combines with
ornithine and carbon dioxide in the mitochondria to form citrulline.
Citrulline is then converted to arginine. In this process, therefore,
ammonia detoxification is elegantly completed. In muscle and liver cells
nitrogen and carbon dioxide produce urea that is finally excreted via
the kidney as urine.
By promoting adequate tissue concentration of adenosine triphosphate
(ATP) and creatine phosphate (a form of ATP), and by recycling lactate
and reducing hydrogen ions, citrulline malate radically boosts energy,
aerobic and anerobic performance, and recovery. This is significant
because intense muscular20exertion leads to the production of lactic
acid. Lactic acid, in turn, creates the so-called “burn” during intense
muscular stress, reducing muscular output and performance and forcing
the athlete to end his routine and recover. So, the removal of lactic
acid from the blood promotes rapid recovery.
Furthermore, citrulline malate plays an important role in the regulation
of nitric oxide. In particular, several benefits from citrulline malate
supplementation are intimately connected to its role in endogenous
regulation of plasma levels of arginine. Specifically, citrulline (malate)
has been shown to be more effective than arginine in boosting endogenous
plasma arginine levels (Yearick et al, 1967).
Altogether, citrulline malate supplementation dramatically boosts
endurance, promotes rapid recovery from intense muscular exertion, and
boosts the synthesis of nitric oxide. Plasmagen Nitrate delivers an
effective dose of citrulline malate to drive you workout intensity and
recovery!
Arginine Ethyl Ester DI-HCL
A conditionally essential amino acid, arginine has several metabolic
functions, one of the central ones being its role in nitric-oxide
synthesis. Others include its beneficial effect on insulin, hormone, and
creatine syntheses. L-Arginine is the substrate for two enzymes,
arginase and nitric oxide synthase. These enzymes compete against each
other for the arginine metabolic pathway. The enzyme arginase converts
arginine to ornithine and urea. Nitric oxide synthase converts arginine
to nitric oxide, the potent vasodilat or. A higher expression of the
arginase enzyme leads to higher ornithine production, but less nitric
oxide production. Now, adenosine, adenine, inosine, uric acid,
citrulline malate, magnesium tanshinoate B, and beta alanine are some of
the known competitive arginase inhibitors. Such arginase inhibition
produces an elevated expression of the nitric-oxide synthase enzyme.
This means even more nitric oxide can be produced from arginine, leading
to stronger vasodilation (and pump). An optimal approach to boosting
nitric-oxide synthesis would, therefore, require a combination of
stimulation of nitric-oxide synthase and arginase inhibition. Several
compounds in Plasmagen Nitrate cover both paths to provide superior
vasodilation and vascularity!
As it turns out, standard arginine (L-Arginine) has several limitations.
First, l-arginine is poorly absorbed and rapidly metabolised in the
intestines, severely compromising its biological action.
The limitations of pure arginine make more advanced forms an imperative.
These advanced arginine forms involve the bonding of arginine to another
compound. Arginine Ethyl Ester HCL (AEE) is a superior arginine form
created by the attachment of an ethyl ester to the arginine molecule.
Esters are formed by the reaction of alcohols and carboxylic acid.
Esterification overcomes the typical arginine limitations by making
arginine less polar, hence easier to absorb in the digestive tract.
Esterification also protects arginine from rapid degradation.
Altogether, in its ethyl-ester form, arginine achieves superior
stability, absorbs dramat ically better, demonstrates impressive
bioavailability, and is able to produce exponential improvements in
arginine’s ergogenic effects. Consequently, relatively small doses of
AEE out-perform supra-physiological doses of standard arginine. Less is
more! In particular, AEE potentiates nitric-oxide synthesis, leading to
dramatically enhanced vasodilation and intense vascularity, flooding
skeletal muscle cells with nutrient and oxygen-rich blood to create an
environment conducive for anabolism. In this connection, arginine also
supports muscle tissue repair (and growth), and consequently, faster
recovery from exercise-induced stress. As an ancillary effect of
nitric-oxide synthesis, arginine improves erectile function and sexual
performance.
Glycine Propionyl-L-Carnitine (GPLC)
Discovered in 1905, carnitine is a water-soluble compound with
structural similarity to vitamins. Carnitine can, not only be
synthesized in small amounts from the amino acid, L-Lysine, but can also
be obtained from meat, fish, and poultry, and plays a crucial role in
fat metabolism. More specifically, carnitine serves as the transport
system for shuttling long-chain fatty acids into the body’s fat-burning
furnace, the mitochondria, where these fatty acids, the primary energy
sources for skeletal muscle and heart cells, are metabolised (burnt) for
cellular energy. Recall that short- and medium-chain fatty acids do not
require a shuttling medium into the mitochondria, as they can penetrate
the mitochondria without the help of a carrier. Carnitine is also
involved in the elimination=2 0of toxic compounds from the mitochondria,
further helping to reach and maintain optimal mitochondrial activity.
Even though carnitine is available from food sources, an individual
could also experience carnitine deficiency that expresses itself in the
form of weakness, muscle pain, and propensity to fatigue.
Carnitine supplementation triggers higher fatty-acid oxidation in heart
mitochondria, and also boosts adenosine tri-phosphate (ATP) and
phosphocreatine (an ATP storage form) levels in heart tissue. By helping
to boost myocardial (heart) metabolism and restore mitochondrial
function and ATP levels, carnitine may help in boosting immune response
and slowing the aging process.
While pure L-Carnitine can power mitochondrial function and cellular
ATP, certain more advanced forms of l-carnitine are known to be
significantly more effective and versatile in many directions than base
carnitine. One of these forms is a potent, novel, and uniquely effective
compound known as Glycine Propionyl-L-Carnitine (GPLC). GPLC is a
propionyl ester of carnitine (PLC) with an additional glycine fraction
that has an enormous affinity for heart, muscle, and endothelial tissue,
leading to dramatic elevations in ATP/creatine-phosphate ATP synthesis
and mitochondrial function (by dramatically improving the shuttling of
fatty acids into the mitochondria to produce cellular energy in muscle
cells, such as the heart), unmistakable improvements in endurance,
delaying of the on-set of fatigue, as well as optimizing glycogen
synthesis for further enhancement in energy and20endurance. Furthermore,
and this is a key part of this blend, GPLC acts like Idebenone (the
potent analog of CoQ10) by directly contributing to the compensation for
reduced availability of oxygen during exercise. Apart from promoting
strength and endurance, GPLC also, like citrulline malate, reduces the
build-up of lactic acid and supports the expulsion of toxic waste
substances; and like beta-alanine and arginine ethyl ester, promotes
superior arterial vasodilation and helps to maintain the structural
integrity of endothelial cells. GPLC can even help in correcting
clinical symptoms of certain cardiovascular conditions. As if the
foregoing were not enough, GPLC helps protect against vascular cell
inflammation much better than other carnitine forms, and may protect
against abnormal heart function common in diabetics. Something else that
may interest you: GPLC, combined with Acetyl-L-Carnitine (ALCAR), was
more effective than testosterone at improving nocturnal penile
tumescence and the International Index of Erectile Function score, an
important measure of erectile and sexual function (Cavallini G, et al:
Carnitine versus androgen administration in the treatment of sexual
dysfunction, depressed mood, and fatigue associated with male aging.
Urology. 2004 Apr;63(4):641-6). This suggests a role for GPLC (stacked
with ALCAR) in the management of male sexual dysfunction.
As you can see, GPLC introduces substantial leverage into Plasmagen
Nitrate by synergistically exponentiating the unique biological
activities of the other agents in the matrix. With GPLC in this formula,
1+1 = 5! You will know when it hits you!
L-2-Aminopentanoic Acid
Also known as L-Norvaline (or L-Nor-Valine), L-2-Aminopentanoic Acid is
a modified form of the branched chain amino acid, L-Valine, with unique
biological effects. Unlike L-Valine, however, L-Norvaline is not
involved in protein synthesis. Instead, L-Norvaline acts as a potent
enzyme inhibitor. In particular, L-Norvaline directly inhibits arginase,
the enzyme that acts to limit the production of nitric oxide. By
inhibiting arginase, L-Norvaline dramatically increases nitric oxide
synthesis, vasodilation, vascularity, muscle hardness and density.
Furthermore, L-Norvaline stabilizes arginine, ensuring that it stays
active longer. Combining the arginase-inhibition action of L-Norvaline
with the nitric-oxide-synthase promoting actions of beta-alanine,
magnesium tanshinoate B, and citrulline malate would shatter your
natural nitric-oxide production limits and ensure your workouts will
never be the same again!
Magnesium Tanshinoate B
Plasmagen Nitrate includes Magnesium Tanshinoate B (MTB) to create a
perfect blend of workout potentiators and recovery agents like no other.
MTB is an active hydrophilic compound purified from the dried root and
rhizome of danshen (Salvia miltiorrhiza), the Chinese herb. MTB, also
known as lithospermic B magnesium salt, or magnesium lithospermate B,
has been used in Traditional Chinese Medicine as an effective medium in
stimulating blood flow, reducing inflammation (pain), eliminating blood
stasis, and achieving a balanced state of mind. Now=2 0you begin to see
why we got interested in this unique compound! In particular, MTB has
been shown to significantly boost nitric oxide production in endothelial
cells, leading to radical elevations in vasodilation and vascular tone.
Besides, MTB’s unique pharmacological actions extend to promotion of
cardiovascular function, inhibition of ischemia and hyperplasia,
inhibition of renal dysfunction, liver damage, and lung fibrosis,
counteraction of mitochondrial dysfunction, depletion of reactive oxygen
species, protection of endothelial cells from low density lipoprotein
oxidation, and boosting of cellular energy. Clearly, MTB is an important
part of Plasmagen Nitrate, acting in synergy with the other agents in
the blend to deliver unparalleled workout intensity, vascular tone,
muscle growth, rapid recovery, and optimised immune function.
Once you try Plasmagen Nitrate, you will never again settle for less!
Challenge us! |
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| *These statements have not been evaluated by the Food & Drug
Administration. This product is not intended to diagnose, treat, cure or
prevent any disease. |
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