Hi-Tech Pharmaceuticals N.O. Overload 310 gm

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Hi-Tech Pharmaceuticals N.O. Overload® - N.O. Overload® is designed to take advantage of the pre-workout "window of opportunity" to promote muscle growth by supporting a feeding pool flourishing with compounds that promote improvements in training intensity, work performance, and to set your muscles up for more rapid recovery and enhanced muscular growth. N.O. Overload® empowers your muscles (throughout your entire training session) not only with the very best that sports supplement science has to offer through support of increased NO production, but also blasts your system with the very best pre-workout compounds known to sports supplement science to support the most dynamic bodybuilding environment imaginable!

      ● Pre-Workout Formulation that Blasts Muscle with Over 30 Compounds!
      ● Utilizes the Novel Approach of Arginase Inhibition to Push the Boundaries of Nitric Oxide Production
      ● Helps Optimize the Mind-Muscle Connection
      ● Supports the Most Dynamic Bodybuilding Environment Imaginable

N.O. Overload™ is the leading pre-workout formula whose unmatched ingredient formulation of over 30 natural compounds helps your body take advantage of the pre-workout window of opportunity to accelerate muscle growth by supporting muscle work performance.

N.O. Overload™ contains Hi-Tech’s Nitric Oxide Blend that combines Micro-Rx™ and Extend-Rx™ Technology with several advanced forms of L-arginine that support nitric oxide (NO). To help safeguard the L-arginine components, N.O. Overload™ utilizes the novel application of arginase (the enzyme that breaks down L-arginine) inhibition (using the arginase inhibitors ABH, BEC, and L-norvaline) to push the boundaries of NO production.

N.O. Overload™ also contains Hi-Tech’s Muscle Cell Volumizing and Work Performance Technology and Hi-Tech’s Recovery Rx™ that incorporate advanced forms of creatine (and other key cell volumizing agents), branched chain amino acids (BCAAs), and L-glutamine to help support intense muscular contraction and set your muscles up for an optimal muscle-building response.

N.O. Overload™ also contains Thermo-Rx® and the Hi-Tech Energy Complex with ingredients that help support the mind-muscle connection to amplify your training intensity throughout your entire workout.

The ingredients in N.O. Overload™ help support the most dynamic pre-workout muscle-building environment imaginable. N.O. Overload™ provides you with the very best that sports supplement chemistry has to offer at the onset of the metabolic window of opportunity that begins when your weight training session kicks off!

We know that N.O. Overload™ is, by far, the very best pre-workout performance stimulator and muscle accelerator available and we back that with a guarantee.

The nitric oxide (NO) sports supplement category has grown to astronomical proportions in recent years, although this is really a pre-workout supplement category that incorporates NO assist ingredients. Although everyone in the sports supplement world is talking about NO, very few people really understand much about it. br>
When the amino acid L-arginine is delivered to the endothelial cells of the inner layer of arterial walls, nitric oxide (NO) is formed via the enzyme nitric oxide synthase (NOS), which means that L-arginine is a precursor of NO. Increased levels of NO cause vasodilation (widening) of blood vessels. This leads to increased blood volume (known in the bodybuilding world as "the pump"), which is sought after by bodybuilders to optimize the grueling exchange of oxygen, glucose, amino acids, creatine, waste by-products of muscular contraction, etc., that takes place both into and out of muscle during and immediately after intense muscular contraction. It might seem logical to conclude that supplementing with L-arginine would enhance the production of NO. However, it’s more complicated than that. The body uses L-arginine for many purposes other than its role as a precursor of NO. Also, according to the PDR® for Nutritional Supplements™, in vitro studies have shown that under normal physiological circumstances NOS is saturated with its L-arginine substrate. In other words, L-arginine would not be expected to be rate-limiting for the NOS enzyme, and it would not appear that supraphysiological levels of L-arginine, which would occur with oral supplementation of L-arginine, would make any difference with regard to NO production. The reaction would appear to have reached its maximum level. However, in vivo studies have demonstrated that under certain physiological conditions, supplemental L-arginine can enhance endothelial-dependant vasodilation and NO production, possibly through mechanisms that interfere with compounds that are normally inhibitors of NOS. This discordance between the in vitro and in vivo results is known as the "arginine paradox."

Scientific data has not yet validated that intense muscular contraction fosters a type of physiological environment that enables supplemental L-arginine to positively influence greater activity of NOS and thus enhanced levels of NO. Despite this lack of scientific support, "real-world" anecdotal evidence, from the stomping grounds in the gyms across America, suggests that NO supplements are contributing to enhanced levels of NO. However, because the formulations in these popular NO products contain many beneficial pre-workout compounds (mostly creatine and other amino acids), which may or may not enhance the production of NO, one cannot discount the extent to which these other compounds may be contributing to the vasodilation effect that has already been initiated by the body in response to intense muscular contraction.

For a moment, let's operate under the assumption that the physiological state resulting from the onset of intense muscular contraction does tip the balance of the “arginine paradox” scale in favor of L-arginine-enhanced NOS activity and NO production. The entire sports supplement industry, in its near insane NO craze, has still completely missed the boat when it comes to creating the best possible NO products, because these product formulations fail to utilize L-arginine effectively to push the real boundaries of NO production. L-arginine is easily broken down by the enzyme arginase before it can be made available to endothelial cells,, which has led other supplement companies to use an “end run” approach - to by-pass arginase by utilizing a precursor of L-arginine called L-arginine alpha-keto-glutarate (AAKG). Unfortunately, this now brings an intermediary compound(s) into the "food chain" of NO production, which may very well result in gross inefficiency in terms of supplying optimal levels of L-arginine to the endothelial cells for NO production. What is lacking in these NO products is the technology that utilizes arginase inhibitors to knock-out arginase enzymes that prevent L-arginine from uniting with NOS enzymes on its way to creating NO.

N.O. Overload® Works!
Hi-Tech Pharmaceuticals, on the other hand, utilizes this very novel pathway of arginase inhibition in its N.O. Overload® Muscle and Strength supplement. N.O. Overload® is exactly what its name says it is... an overload of NO! But that's only the beginning. N.O. Overload® is jacked with over 30 ingredients that were carefully selected by the Hi-Tech Pharmaceuticals Research and Development team after digging deep into the trenches of scientific literature for the most promising natural approaches to build muscle and strength, particularly in the area of optimizing muscle cell work performance. The ingredient compounds that made the final cut for the N.O. Overload® formulation include three arginase inhibitors, nine muscle cell volumizing and work performance technology compounds, five NO drivers with Micro-Rx™ and Extend-Rx™ Technology, six energy complex components, and four amino acid recovery agents.

N.O. Overload® is designed to take advantage of the pre-workout "window of opportunity" to promote muscle growth by supporting a feeding pool flourishing with compounds that promote improvements in training intensity, work performance, and to set your muscles up for more rapid recovery and enhanced muscular growth. N.O. Overload® empowers your muscles (throughout your entire training session) not only with the very best that sports supplement science has to offer through support of increased NO production, but also blasts your system with the very best pre-workout compounds known to sports supplement science to support the most dynamic bodybuilding environment imaginable!

*These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.